STAGES

A computer model of the seminiferous epithelium cycle

Track germ cells through spermatogenesis — forward and backward in time — across 21 species, from rat and mouse to human, bull, horse, and beyond.

STAGES is an interactive teaching and research tool for reproductive biology, toxicology, and veterinary science. Pick a species, pick a cell, and predict where it will be after any number of days. Useful for identifying target cell types in toxicity studies, planning sampling, and teaching the kinetics of the cycle.

What it does

Forward and backward prediction of germ cell positions across the cycle
Adjustable cycle length and stage frequencies per species
Stage histology images with cell labels and schematic drawings
Decision tree, manuscripts, and references built in
Runs in any modern browser — Mac, Windows, Linux, iPad, Chromebook

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Built on the work of

Hess RA (1990). Quantitative and qualitative characteristics of the stages and transitions in the cycle of the rat seminiferous epithelium: light microscopic observations of perfusion-fixed and plastic-embedded testes. Biology of Reproduction 43(3): 525–542.